LifeMine Therapeutics
LifeMine Therapeutics is reinventing drug discovery by mining genetically-encoded small molecules (GEMs) from the biosphere. Through our evolutionarily-derived genomic drug discovery platform, Avatar-Rx, LifeMine aims to bring unparalleled speed, predictability, and scalability to drug discovery. LifeMine has discovered, in genomic space, hundreds of potentially high-impact drug candidates relevant to targets across all major disease areas and has an initial focus on advancing highly impactful precision medicines in oncology and immune modulation.
Headquartered in Cambridge, Massachusetts, USA, LifeMine is opening its European Headquarters in Basel. Our 4,000 m2 facility is in Klybeck, Basel, right next to the beautiful Rhine River and the train station, close to City Center. The Klybeck area is home to many top US and Swiss pharmaceutical and Biotech companies in Europe’s biotechnology hub.
Summary
We are seeking a highly motivated Scientist I/II to join our growing Chemical and Exploratory Cell Biology team located in Basel, CH. The ideal candidate will have made substantial contributions to drug discovery research, ideally in the oncology space, including involvement in assay development.
Responsibilities
Supporting the biological validation of novel drug targets, sharing ideas, and influencing LifeMine’s target selection within a team of scientists
Running assays to address key biological questions to drive drug discovery
Fostering collaboration between interdisciplinary teams of scientists to efficiently identify novel lead molecules and transition them into the clinic
Executing experiments to explore the activity and mode of action of novel drug candidates to support our portfolio projects
Accurately recording, analyzing, interpreting, and presenting data to the internal team and other stakeholders
Maintaining trustful relationships with external CROs to pursue our shared research goals
Requirements
Ph. D. in Biology, Biochemistry or Chemical Biology with 0-2 years drug discovery experience
Demonstrated track record of providing significant biological insights to drug discovery efforts, especially in the areas of oncology and cell signaling
Expertise in cellular and molecular biology techniques including mammalian cell culture, flow cytometry, RNAi, CRISPR, qPCR, Western blotting, and microscopy
Experience in optimizing medium- to high-throughput cell-based mechanistic and in vitro/ex vivo functional assays
Familiarity with state-of-the-art cell assay technologies e.g. AlphaLISA, HTRF, MSD, In-Cell Western, etc.
Excellent problem-solving, multi-tasking, organizational, and communication skills
Ability to work independently and collaborate in a dynamic and team-oriented environment
To apply for this job please visit lifeminetx.com.