2023 Summer Internship – Process Development

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About The Role

Job Description

At Takeda, we are committed to lifelong learning.

To that end, Takeda’s summer internship program blends real world experience with an extensive overview of the pharmaceutical industry. Knowledgeable mentors will provide guidance as you gain professional hands-on experience to start your career or further develop in your expertise.

The summer internship program is a full-time commitment of 12 weeks in length and offers a unique perspective into a world-class pharmaceutical company. Our internship program also provides you the opportunity to network with people at Takeda through various planned events and activities.

Project Outline

Current state of automation with respect to ambr15 perfusion operations and protein capture require significant manual handling which requires increased time per run and introduces additional contamination risk. Protein capture requires at least RoboColumn purification which is only capable of running eight samples in parallel and takes half a day. Additionally, non-Fc domain proteins require bench-scale purification since specific affinity resin is used. Linking our ambr15 operations to automated uncapping/capping and media replacement for scale-down perfusion mimic and establishing a workflow for automated 96-well plate-based purification would significantly reduce time requirements, allowing for more efficient process development.

Under the supervision of a process engineer within Process Development, the intern will contribute to two main objectives: (1) Integration of automated ambr15 capper and media replacement; (2) Establish workflow for automated plate-based purification. Techniques involved include Tecan liquid handler automation and scripting, small-scale protein production, and sampling by ambr15 HT bioreactor system. The intern will have the opportunity to present research findings to other stakeholders within PD-US at the end of the summer.

How You Will Contribute

• Deadline-driven with a high level of organizational and planning skills
• Strong analytical, problem-solving, and oral and written communication skills
• Ability to work well in teams, effectively manage projects, and present ideas clearly and concisely.
• Global mindset to grow in a diverse work environment
• Excellent communication and leadership skills
• Theoretical knowledge of protein production and separations, basic knowledge of computer programming
• Self-starter and be comfortable working in the laboratory, with some direction of a Staff Engineer.
• Desired major: Life Sciences major (Chemical Engineering, Biology, Biochemistry, Bioengineering, etc.)

Requirements / Qualifications

As stated above, Takeda is committed to lifelong learning opportunities. To that end, our internship program is open to currently enrolled students seeking early experiences and non-traditional candidates interested in making a career change and gaining new experience.

The requirements for these two groups of candidates are specified below:

Candidates Currently Enrolled At An Accredited University

• Must be authorized to work in the US without sponsorship (i.e., Takeda will not sponsor interns)
• Must be available to work full-time (40 hours/week), within core business hours (8 AM-5 PM), for a minimum of 12 weeks during the summer months
• Minimum GPA 3.0/4.0
• Undergraduate, Graduate, PhD, MD student with at least one year of university studies before internship
• Return to university for at least one semester post-internship
• Takeda does not provide student housing or housing stipends

Non-traditional Candidates Not Currently Enrolled At University

• Must be authorized to work in the US without sponsorship (i.e., Takeda will not sponsor interns)
• Must be available to work full-time (40 hours/week), within core business hours (8 AM-5 PM), for a minimum of 12 weeks during the summer months
• Must provide a cover letter explaining why you are seeking this internship, relevant experience that makes you a good candidate, and what you hope to achieve through the experience
• Strong preference for non-traditional candidates with some experience relevant to the desired intern role

EEO Statement

Takeda is proud in its commitment to creating a diverse workforce and providing equal employment opportunities to all employees and applicants for employment without regard to race, color, religion, sex, sexual orientation, gender identity, gender expression, parental status, national origin, age, disability, citizenship status, genetic information or characteristics, marital status, status as a Vietnam era veteran, special disabled veteran, or other protected veteran in accordance with applicable federal, state and local laws, and any other characteristic protected by law.

Locations

Lexington, MA

Worker Type

Employee

Worker Sub-Type

Paid Intern (Fixed Term) (Trainee)

Time Type

Full time