FoRx Therapeutics is a preclinical, privately held company based in Basel, Switzerland. FoRx focuses on drugging key molecular targets involved in the DNA Replication Stress pathway, as a new approach in the development of targeted anti-cancer drugs. The company is backed by a strong syndicate of investors that include the Novartis Venture Fund, Pfizer Ventures, M Ventures, Omega Funds and LSP Venture Capital. This new position was created to strengthen our medical chemistry development. Location: Basel, Novartis Campus

Tasks

• Provide medicinal chemistry expertise in the hit finding, hit-to-lead and lead optimization phases in close collaboration with internal and external partners.
• Design innovative small molecule to enable rapid multi-parameter optimization of hits and leads with the ultimate goal to deliver clinical candidates.
• Application of state-of-the-art technology and current best practice in medicinal chemistry.
• Work closely with external chemistry CRO teams to synthesize and screen small molecules.
• Work collaboratively across scientific disciplines like computational chemistry on multiple projects providing important input on medicinal chemistry aspects.
• Perform IP analyses and secure company´s IP by patent filing.
• Help to build and expand an innovative drug discovery platform.

Requirements

• Ph.D. and postdoctoral experience in Organic Chemistry with >7 years of industry experience as a medicinal chemist.
• Demonstrated track record of advancing drug discovery programs from early discovery to IND filing.
• Experience in managing, directing and prioritizing the work of remote teams of medicinal and synthetic chemists at CROs.
• Practiced in assessing the IP landscape and filing patent applications.
• Highly organized, detail-orientated with excellent communication skills.
• Proactive, forward-thinking and problem-solving attitude.
• Strong team player.
• Fluent in written and spoken English.

Benefits

• Exceptional possibilities for the discovery of innovative anti-cancer drugs
• Highly dynamic and motivated team with flat hierarchies
• Competitive salary and excellent package of additional benefit
• Possibility of partial remote work